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Scientists name safest blood thinning drug, Apixaban
According to Annals of Internal Medicine, researchers from University College London named apixaban as the safest blood-thinning drug. The researchers say that anticoagulants are given to patients with atrial fibrillation to prevent blood clots and strokes and GI bleeding is one of the most common side effects of taking them.
Researchers examined data from nearly 500,000 patients in the United Kingdom, France, Germany, and the United States in a large new study to assess the effectiveness and risk of side effects of the four most commonly used anticoagulants: apixaban, dabigatran, edoxaban, and rivaroxaban. They discovered that the efficacy of all four drugs in preventing ischemic stroke and all-cause mortality was comparable. At the same time, apixaban had a 19-28% lower risk of gastrointestinal bleeding than the other three drugs.
The scientists' findings held true when they looked at data from people over the age of 80 and those with chronic kidney disease.
If the authors' findings are supported by randomised controlled trials, apixaban may be recommended for patients at high risk of bleeding who require anticoagulants.